I recently put in 3 new ink tanks and suddenly the print quality started fading. Head cleaning seemed to make it worse until there was barely even any black ink printing. I was just about to scrap it and take out one the CX6600s or CX6000s that I have in reserve when I remembered seeing a post a while back about the overflow tubes clogging and creating a similar outcome. I removed the small access panel on the back of the printer and found 2 tubes connected to a plastic 90° elbow. I removed the hose clamps and took the tubes from the elbow and found it was clogged. This apparently is the overflow where the excess ink goes after passing the print heads. I cleaned the elbow with hydrogen peroxide until I could blow through it (and for good measure blew it out with the 150psi Craftsman compressor) and then dipped a toothpick into the hydrogenP and inserted it into both tubes as far as it would reach. I was able to pull out some thick blackened ink from both tubes and the HydrogenP seemed to disolve it quickly. I reassembled everything and had to run the head cleaning program 3 or 4 times and now to my surprise it is printing like brand new. I'm a little pissed that I had to waste so much ink in the cleaning process but luckily I picked up a chip resetter on clearance at Staples a while back and used it for the first time. It worked as advertised and now I just have to be sure to manually monitor the ink tanks and replace them before the print heads run dry.
So if you have an Epson AIO that starts acting up, before you trash it, give this method a try.